Tuesday, January 9, 2018

Ibuprofen may have a new side effect.

How High Doses of Ibuprofen May Impact Male Infertility

Men who take relatively high doses of ibuprofen may be at increased risk for fertility problems, early research suggests. The small study, which was published yesterday (Jan.

From article, (Men who take relatively high doses of ibuprofen may be at increased risk for fertility problems, early research suggests.
The small study, which was published yesterday (Jan. 8) in the journal Proceedings of the National Academy of Sciences, found that men who took 1,200 milligrams of ibuprofen a day for six weeks developed a hormonal condition that is linked with reproductive problems.
The study involved 31 men (ages 18 to 35) who were randomly assigned to take ibuprofen (two doses of 600 mg each) or a placebo every day for six weeks.
The researchers found that, compared with the placebo group, the men who took ibuprofen experienced a 23 percent increase in levels of luteinizing hormone (LH) — a hormone that's secreted by the pituitary gland and stimulates the production of testosterone — after two weeks. Higher-than-normal levels of luteinizing hormone can indicate a problem with the testes, according to the National Institutes of Health.
However, despite the change in LH levels, the men's testosterone levels didn't change. This indicates that they had developed a condition called "compensated hypogonadism," which happens when testosterone production is reduced, but the body is able to compensate by increasing LH levels, the researchers said.
Compensated hypogonadism is typically found in older men, and it is linked with impaired fertility, according to the study.)
Me, "This does not mean men should stop using Ibuprofen. It means if you're trying to get your wife pregnant? You should avoid using this drug until after she is. What it also means is that there may be a lot of approved, chemicals out there, that could be affecting human reproduction. Its basically buyer beware. For every good result of a med, there could be a bad result too."

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