Vitamin C Might Shorten Tuberculosis Treatment Time, Study Indicates
A new study has found that anti-tuberculosis drugs killed more bacteria in laboratory mice given a vitamin C supplement than those given drugs alone. If the findings hold up in human studies, the authors say, the result could be that there's a cheap, safe way to reduce the months-long treatment time for one of the world's leading killers.
From article, (Albert Einstein College of Medicine microbiologist William Jacobs and colleagues previously discovered by accident that antioxidants like vitamin C stopped TB bacteria in a test tube from becoming persisters.
"When we first discovered it, it was like, 'Wow! There's just so much we don't know yet. And wouldn't that be really cool if it really works,' " Jacobs said.
The study in the journal Antimicrobial Agents and Chemotherapy said Jacobs and colleagues found that TB-infected mice treated with two standard drugs plus a high dose of vitamin C had roughly tenfold fewer bacteria in their lungs after several weeks than mice treated with drugs alone.
"It's not sterilization yet," he added, "but it's heading in that direction."
But will it work in people?
"The bottom line is that we don't know the answer," Jacobs acknowledged. "But I think what this study suggests is we should really go and [find out]."
Other experts not connected to the study agreed.)
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